Stroke genomics

methods and reviews
  • 351 Pages
  • 0.32 MB
  • English

Humana Press , Totowa, N.J
Cerebrovascular disease -- Genetic aspects., Cerebrovascular disease -- Molecular aspects., Genomics., Cerebrovascular Accident -- gene
Statementedited by Simon J. Read, David Virley.
SeriesMethods in molecular medicine -- 104
ContributionsRead, Simon J., Virley, David.
LC ClassificationsRC388.5 .S85254 2005
The Physical Object
Paginationx, 351 p. :
ID Numbers
Open LibraryOL21802167M
ISBN 101588293335, 1592598366
LC Control Number2004012019

Cutting-edge and highly practical, Stroke Genomics: Methods and Reviews shows how to successfully design, execute, and interpret preclinical and clinical molecular biological studies of stroke, work that will greatly advance its understanding, as well as rapid development of the Format: Hardcover.

Cutting-edge and highly practical, Stroke Genomics: Methods and Reviews shows how to successfully Stroke genomics book, execute, and interpret preclinical and clinical molecular biological studies of stroke, work that will greatly advance its understanding, as well as rapid development of the.

In book: Cardiovascular Genetics and Genomics, pp - Cite this publication. Mark J Alberts ORs for stroke were (95% CI to ), (95% CI to ) and (95% CI 3.

Details Stroke genomics FB2

When the human genome was sequenced inthe implications for cardiovascular and stroke medicine—in terms of the new diagnostic, therapeutic, and preventive strategies that may ultimately result—were immediately recognized (1, 2).Genetic and genomic factors appear to contribute to all stages of the development of vascular disease, from predisposition, through risk and subclinical Cited by: H1 H2 H3 H4 H5 H6 Our focus is the diseases affecting the blood vessels of the brain, known as cerebrovascular disease.

Among the leading causes of death and disability worldwide, these diseases are collectively responsible for strokes, gait problems, cognitive decline and depression and are the most common causes of deterioration in brain function [ ].

Introduction to stroke genomics / Simon J. Read and Frank C. Barone --Choice, methodology, and characterization of ischemic stroke models: the search for clinical relevance / Stroke genomics book Virley --Mutant animal models of stroke and gene expression: the stroke prone spontaneously hypertensive rat / Hilary V.O.

Carswell [and others] --Gene therapy in. Stroke is a leading cause of death and a major cause of disability in the United States. A stroke occurs when the blood supply to part of the brain is blocked, or when a blood vessel in the brain bursts, causing damage to a part of the health conditions and behavioral and lifestyle factors can put individuals at a higher risk for stroke.

Description Stroke genomics EPUB

In Stroke Genomics: Methods and Reviews, leading experts in the field explore the pragmatic application of the tools of genomic and molecular biology research to the treatment of stroke.

Providing the reader with cutting-edge reviews of clinical and preclinical genomics, the authors relate changes in gene expression to physiological end points. Genomic and Personalized Medicine, Second Stroke genomics book — winner of a Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action.

As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based. Stroke Genomics by Simon J. Read,available at Book Depository with free delivery worldwide.

Stroke genetics includes several topics of clinical interest, including (1) molecular genetic variations affecting risk of monogenic stroke syndromes; (2) molecular genetic variations affecting risk of common stroke syndromes, sometimes with specific effects on risk of specific main types of stroke or subtypes of ischemic and hemorrhagic stroke; (3) genetics of conditions associated with Cited by: Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm.

The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular. Our Publications.

Publications from Dr. Jonathan Rosand and Dr. Chris Anderson April, “When scientists underestimate complexity, they fall prey to the perils of unintended consequences.

The parables of such scientific overreach are well-known: foreign animals, introduced to control pests, become pests in their own right; the raising of smokestacks, meant to alleviate urban pollution, releases particulate effluents higher in the air and exacerbates pollution; stimulating blood.

Molecular Genetics of Stroke (Colloquium Series on Genomic and Molecular Medicine) [Yoshiji Yamada] on *FREE* shipping on qualifying offers.

Stroke is an important clinical problem because of its large contribution to mortality. The main causal and Author: Yoshiji Yamada.

Stroke has attracted global attention, as one in six people will develop stroke in their lifetime,14 Stroke is a significant medical and public health problem, with loss of productivity and burden on families, caregivers and society The lifetime risk of stroke is one in five women and one in six men Stroke is the most common cause.

Purchase Clinical Genomics - 1st Edition. Print Book & E-Book. ISBN  If you want to include Bioinformatics in that, then the best book I have seen so far is this one: Bioinformatics and Functional Genomics: Jonathan Pevsner: : Books This book is a more general introduction to Genomics and i.

Genomics Books Our high level genomics books bring together expert international authors under the skilled editorship of leading scientists to produce state-of-the-art compendiums of current research. Aimed at the research scientist, graduate student, medical reseacher and other professionals, these books are highly recommended for all genomics.

Evidence for a genetic basis for stroke comes from twin and family studies and from the occurrence of a number of uncommon monogenic disorders, but the contribution of genetic factors identified for stroke so far is small. Advances in genetics and genomics may permit new insights. In recent genome-wide association studies, a number of single-nucleotide polymorphisms have been Cited by: Publishing is our business.

Read Free Content. Coronavirus. Springer Nature is committed to supporting the global response to emerging outbreaks by enabling fast and direct access to the latest available research, evidence, and data. Stroke is an umbrella term for the rapid loss of neurologic function in a particular vascular territory, with symptoms lasting greater than 24 hours.

The causes of stroke. This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic.

Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this.

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The Book Introduction to Computational Genomics. A Case Studies Approach. Nello Cristianini University of Bristol. Matthew W. Hahn Indiana University, Bloomington. Cambridge University Press, Hardback and Paperback (ISBN | ISBN ).

The need for genetics/genomics. literacy in cardiovascular/stroke care. Donna K. Arnett, PhD, MSPH. President. American Heart Association/ American Stroke Association. The Stroke Book, Drs. Selim and Torbey have provided an excellent introductory book that overviews all of the burgeoning aspects of cerebrovascular medicine in a File Size: KB.

Principles of Gene Manipulation and Genomics SEVENTH EDITION S.B. Primrose and R.M. Twyman POGA01 12/8/05 AM Page iii. Since then, the ISGC has held one international workshop every six months, hosted by ISGC members from around the world, and has become an international, multidisciplinary network of more than stroke genetics investigators, representing over 20 countries in 5 continents.

An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30, genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease.

This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. Genomics in stroke Fact or fiction. Hugh Markus.

Advances in genotyping Genotyping array Up to 5 million SNPs Candidate gene association study HDAC9 associated with large vessel ischemic stroke The International Stroke Genetics Consortium (ISGC)I & the Wellcome Trust Case Control Consortium 2.

Hi Daniel, this comes to mind: Intro to Bioinformatic Programming Using Python by Orielly from Ben. Ps. I came into bioinformatics the same way, and found wikipedia, this forum,and review articles to be my primary resources.Genetics of stroke. Article Literature Review in Current Atherosclerosis Reports 11(3) June with 8 Reads How we measure 'reads'Author: Myriam Fornage.A stroke occurs when blood flow to a part of the brain suddenly stops.

A stroke is sometimes called a "brain attack or cerebrovascular accident. " If blood flow is cut off for longer than a few seconds, the brain cannot get nutrients and oxygen.

Brain cells can die, causing lasting damage. Risk factors are things that increase your chance of.